By Kivie Moldave

Nucleic acids are the basic construction blocks of DNA and RNA and are present in nearly each residing mobile. Molecular biology is a department of technology that reviews the physicochemical houses of molecules in a cellphone, together with nucleic acids, proteins, and enzymes. elevated knowing of nucleic acids and their position in molecular biology will additional some of the organic sciences together with genetics, biochemistry, and telephone biology. Progress in Nucleic Acid examine and Molecular Biology is meant to deliver to gentle the newest advances in those overlapping disciplines with a well timed compilation of reports comprising each one quantity. * presents a discussion board for dialogue of recent discoveries, methods and concepts in molecular biology * contains contributions from the leaders within the box * Has plentiful references

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Progress in Nucleic Acid Research and Molecular Biology, Vol. 74

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Cohen, E. , and Tanner, J. E. (2000). Activation of transcription factors NF-kappa B and NF-IL-6 by human immunodeficiency virus type 1 protein R (Vpr) induces interleukin-8 expression. J. Virol. 74, 4658–4665. 98. , Owen, J. , Johnson, K. , and Richmond, A. (1997). Mechanism and biological significance of constitutive expression of MGSA=GRO chemokines in malignant melanoma tumor progression. J. Leukoc. Biol. 62, 588–597. 99. Wood, L. , and Richmond, A. (1995). Constitutive and cytokine-induced expression of the melanoma growth stimulatory activity=GRO gene requires both NF-B and novel constitutive factors.

Chem. 276, 45780–45790. 182. Luong, M. , van der Meijden, C. , Monuki, E. , Jones, S. , Lian, J. , Stein, J. , Stein, G. , Neufeld, E. , and van Wijnen, A. J. (2002). Genetic ablation of the CDP=Cux protein C terminus results in hair cycle defects and reduced male fertility. Mol. Cell. Biol. 22, 1424–1437. 183. , Litchfield, D. , and Nepveu, A. (1998). DNA binding by cut homeodomain proteins is down-modulated by casein kinase II. J. Biol. Chem. 273, 2561–2566. 184. , and Nepveu, A. (1998). The mammalian Cut homeodomain protein functions as a cell-cycle-dependent transcriptional repressor which downmodulates p21WAF1=CIP1=SDI1 in S phase.

Chem. 270, 30619–30626. 100. , and Matsushima, K. (1994). Molecular mechanism of interleukin-8 gene expression. J. Leukoc. Biol. 56, 554–558. 32 amiri and richmond 101. , and Lutter, R. (1998). Enhanced AP-1 and NF-kappaB activities and stability of interleukin 8 (IL-8) transcripts are implicated in IL-8 mRNA superinduction in lung epithelial H292 cells. Biochem. J. 330, 429–435. 102. , and Akira, S. (1993). Transcription factors NF-IL6 and NF-kappa B synergistically activate transcription of the inflammatory cytokines, interleukin 6 and interleukin 8.

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