By Gustavo Maroni

Drosophila, the typical fruit fly, is the main generally studied of all organisms from the point of view of genetics and cytology. This atlas summarizes what's identified in regards to the nearly a hundred Drosophila genes for which the full nucleotide series is understood. every one access incorporates a description of the gene's molecular association and expression, the entire nucleotide and amino acid sequences, maps of fascinating constructions, highlights of useful gains and promoter regulatory areas, and chosen references to the first literature. A separate part of the atlas considers diversified points of gene association as they take place within the Drosophila genome. themes lined contain dimension correlations between a variety of genetic parts, splicing signs, translation initiation indications, and codon bias. The paintings represents a brand new milestone in summarizing present details and making it simply available to geneticists and biologists.

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Extra info for An Atlas of Drosophila Genes: Sequences and Molecular Features

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And Craig, E. A. (1988). Molecular and genetic characterization of the Drosophila melanogaster 87E actin gene region. Genetics 119:407-420. , Maekawa, H. and Hotta, Y. (1986). Molecular characterization of mutant actin genes which induce heat-stock proteins in Drosophila flight muscles. EM BO J. 5:589-596. Rao, J. , Zafar, R. S. and Sodja, A. (1988). Transcriptional activity at the 3' end of the actin gene at 5C on the X chromosome of Drosophila melanogaster. Bioch. Biophys. Acta 950:30-44. , Tobin, S.

This observation led to the suggestion that gene conversions 44 FIG. 1. Comparison of the mouse (Accession, V00718) and Drosophila (Dm) Amy A sequences. There is 55% overall identity between the two proteins. Sequences aligned with the GCG Pileup program. 46 AN ATLAS OF DROSOPH1LA GENES FIG. 2. The two Amy genes. in the coding regions maintain a high degree of conservation (Hickey et al. 1991). AmyA Gene Organization and Expression Open reading frame, 494 amino acids; predicted mRNA length, 1,601 bases.

Manseau, L. , Ganetzky, B. and Craig, E. A. (1988). Molecular and genetic characterization of the Drosophila melanogaster 87E actin gene region. Genetics 119:407-420. , Maekawa, H. and Hotta, Y. (1986). Molecular characterization of mutant actin genes which induce heat-stock proteins in Drosophila flight muscles. EM BO J. 5:589-596. Rao, J. , Zafar, R. S. and Sodja, A. (1988). Transcriptional activity at the 3' end of the actin gene at 5C on the X chromosome of Drosophila melanogaster. Bioch. Biophys.

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